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UCL Mechanical Engineering
Faculty of Engineering Sciences

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MECHGB04 Applications of Biomedical Engineering

The course aims to impart knowledge of the latest applications in the wide area of biomedical engineering such as drug delivery, cardiovascular engineering, biophysics, dental materials, orthopaedic engineering.

Code MECHGB04
Alt. Codes(s) None
Title Applications of Biomedical Engineering
Level  M
UCL Credits/ ECTS
Start
End
Taught by Professor Mohan Edirisinghe (Module Coordinator)
Dr Ben Hanson
Dr Suwan Jayasinghe

Plus external lecturers from UCL Eastman Dental School,

UCL School of Pharmacy, Orthopaedic Research (UK),

and from clinical practice

 

Prerequisites

  • At least a 2-ii degree in Science, Engineering or a degree in Medicine.
  • All candidates must satisfy UCL’s English Language requirements.

Content

The lectures of this module are delivered by UCL lecturers and other visiting experts. The module will include contributions from the Furlong Research Charitable Foundation, Eastman Dental Institute, UK industry, foreign & UK university visiting speakers, UCL visiting and honorary professors and research & academic staff of the department of Mechanical Engineering.

Examples of components delivered under the theme of this module: 

  • Drug Delivery & Targeting: This series of lectures will include the general principle and state-of-the-art of drug delivery and targeting, role of liposomes, noisomes, pharmaceutical nanoparticles, polymers and gene therapeutics. Several new methods useful for drug delivery capsule preparation, scaffold deposition, multilayer coating and microbubbling have been developed in the Department of Mechanical Engineering and the School of Pharmacy at UCL. A summary of these new developments will be described in these lectures.

 

  • Cardiovascular Engineering: This part of the module looks at the heart as a complex and efficient electrically-controlled mechanical pump. We investigate its function from a mechanical point of view and consider the implications of various heart diseases. We then review ways in which engineers have attempted to restore the performance of weakened or failing hearts. Students investigate these issues using a computer-based model of the cardiovascular system. Topics covered include: Cardiovascular mechanics, Modelling heart diseases and their consequences, Cardiac assist devices and pacemakers.

 

  • Biophysics: These lectures will endeavour to cover the current status quo and on-going developmental studies carried out with a molecular biology approach, which has exploited the physical sciences. The course will introduce, in particular, and in detail all the associated fundamentals of florescent activated cell sorting (FACScan) with particular emphasis on flow cytometry, thus covering all the closely linked science and technology connected with both hydrodynamics (fluid focusing) and lasers to those novel approaches for de-clustering/agglomerating cellular clumps through advances in fluid dynamics. This section will not only introduce research and developmental aspects of florescent activated cell sorting, but will proceed to demonstrate medical relevance for a wide range of cellular/tissue malignancies in a clinical setting.
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