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UCL Mechanical Engineering
Faculty of Engineering Sciences

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MECH0040 Applications of Biomedical Engineering

MECH0040 Applications of Biomedical Engineering

FHEQ Level:
7 (Undergraduate Yr 4 / MSc)
Term:
Terms 1 and 2
UCL / ECTS Credits:
15 UCL / 7.5 ECTS
Previous Module Code:
MECHGB04 / MECHMB04
Alternative Module Code:
This module is offered to Term 1 affiliate students under the code MECH0041
Prerequisites:
None

Taught By

This module is taught by contributors from the Department of Mechanical Engineering, as well as external lecturers from UCL Eastman Dental Institute, UCL School of Pharmacy, Orthopaedic Research UK, and from clinical practice.

Professor Mohan Edirisinghe (Module Coordinator):
Mohan Edirisinghe
Dr Ben Hanson:
Ben Hanson
Professor Suwan Jayasinghe:
Suwan Jayasinghe

Module Overview

This module aims to impart knowledge of the latest applications in the wide area of biomedical engineering such as drug delivery, cardiovascular engineering, biophysics, dental materials, and orthopaedic engineering. The lectures are delivered by UCL lecturers and other visiting experts. The module will include contributions from the Orthopaedic Research UK, UCL School of Pharmacy, Eastman Dental Institute, UK industry, foreign & UK university  visiting speakers, UCL visiting and honorary professors and research & academic staff from the Department of Mechanical Engineering.

Examples of components delivered under the theme of this module include:

Drug Delivery & Targeting: This series of lectures includes the general principle and state-of-the-art of drug delivery and targeting and is delivered by the UCL School of Pharmacy. Several new methods useful for drug delivery capsule preparation, scaffold deposition, multilayer coating and microbubbling have been developed in the Department of Mechanical  Engineering at UCL. A summary of these new developments is described in other lectures. This later section also includes laboratory demonstrations and these are compulsory.

Cardiovascular Engineering: This part of the module looks at the heart as a complex and efficient electrically-controlled mechanical pump. We investigate its function from a mechanical point of view and consider the implications of various heart diseases. We then review ways in which engineers have attempted to restore the performance of weakened or failing hearts. Students investigate these issues using a computer-based model of the cardiovascular system. Topics covered include: Cardiovascular mechanics, Modelling heart diseases and their consequences, Cardiac assist devices and pacemakers.

Biophysics: These lectures endeavour to cover the current status quo and on-going developmental studies carried out with a molecular biology approach, which has exploited the physical sciences. The course introduces, in particular and in detail, all the associated fundamentals of florescent activated cell sorting (FACScan) with particular emphasis on flow cytometry, thus covering all the closely linked science and technology connected with both hydrodynamics (fluid focusing) and lasers to those novel approaches for de-clustering/agglomerating cellular clumps through advances in fluid dynamics.

The module not only introduces research and developmental aspects of florescent activated cell sorting, but proceeds to demonstrate medical relevance for a wide range of cellular/tissue malignancies in a clinical setting.

Method of Instruction

This module is taught through:

  • Lectures
  • Tutorials
  • Practical laboratory classes

Assessment

This module is assessed entirely through an unseen written examination.

For more information about assessment please contact mecheng.pg-queries@ucl.ac.uk.

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